YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12.
نویسنده
چکیده
Exogenous thymine must be converted to thymidine to enable a thyA (thymidylate synthase) mutant to grow. The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 189 5 شماره
صفحات -
تاریخ انتشار 2007